@article{421, author = {Uri Hasson and Yuval Nir and Ifat Levy and Galit Fuhrmann and Rafael Malach}, title = {Intersubject synchronization of cortical activity during natural vision}, abstract = {
To what extent do all brains work alike during natural conditions? We explored this question by letting five subjects freely view half an hour of a popular movie while undergoing functional brain imaging. Applying an unbiased analysis in which spatiotemporal activity patterns in one brain were used to {\textquotedblleft}model{\textquotedblright} activity in another brain, we found a striking level of voxel-by-voxel synchronization between individuals, not only in primary and secondary visual and auditory areas but also in association cortices. The results reveal a surprising tendency of individual brains to {\textquotedblleft}tick collectively{\textquotedblright} during natural vision. The intersubject synchronization consisted of a widespread cortical activation pattern correlated with emotionally arousing scenes and regionally selective components. The characteristics of these activations were revealed with the use of an open-ended {\textquotedblleft}reverse-correlation{\textquotedblright} approach, which inverts the conventional analysis by letting the brain signals themselves {\textquotedblleft}pick up{\textquotedblright} the optimal stimuli for each specialized cortical area.
}, year = {2004}, journal = {Science}, volume = {303}, chapter = {1634-1640}, doi = {10.1126/science.1089506}, }